Wikipedia
Search Wikipedia:

August 2017
MonTueWedThuFriSatSun
 123456
78910111213
14151617181920
21222324252627
28293031   

Calendar Calendar

Free Hit Counter

Sharpless' click chemistry

View previous topic View next topic Go down

Sharpless' click chemistry

Post  aze on Tue Sep 13, 2011 5:59 am

Hello all,

I've seen that a few years ago, Sharpless published an extremely great method for triazole synthesis, using "click chemistry".
He even showed that an enzyme (acetylcholinesterase) could promote the synthesis of its own inhibitor, with a Kd of 77 fM, the best affinity ever !
The papers were between 2002 to 2005 I think.

But till then, no other papers about this molecule seem to have been published.

Does anyone have more info ? Any other biological tests than in vitro ? Any in vivo results ? In human ? Any patent ?

Anything ?


Thanks !!

aze

Posts : 1
Join date : 2011-09-13

View user profile

Back to top Go down

View previous topic View next topic Back to top

- Similar topics

 
Permissions in this forum:
You cannot reply to topics in this forum